The extract of Scutellaria baicalensis could prevent hepatic fibrosis by promoting ERK-p53 pathways, which may in turn cause G2/M cell cycle arrest and activate the Caspase system, finally resulting in apoptosis of HSC-T6 cells 122. As a result, Scutellaria baicalensis might be beneficial for the amelioration of liver fibrosis. Kudzu root is rich in antioxidants, compounds that protect cells from oxidative stress that can lead to disease.

Dosage and Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others. Dry Mouth Dry mouth, also known as xerostomia, can occur as a side effect of kudzu use.

How do I treat a mouth ulcer?

In addition, participants reported pill taking by checking time-of-day boxes on daily diaries and by entries on the wrist actigraphy watches. A total of 21 adult males (17 Caucasian, 1 African American, 2 Hispanic, 1 Middle Eastern; mean age 23.8 ± 3.46 years, range 21–33) were recruited through advertisements in local and college newspapers and flyers posted in the kudzu extract for alcoholism Boston area. Persons who responded to these advertisements were given a brief telephone screen, and invited to the laboratory for further evaluations. Persons of Asian descent were excluded because of their known increased flushing reaction to alcohol. Individuals with a body mass index (BMI) outside the range of 18–25 kg/m2 were also excluded. Because prescription medications are not universally used or have a perceived modest effect (Krystal et al., 2001; Mark et al., 2003), providing heavy drinkers with any type of intervention that yields even a modest reduction in drinking is desirable.

• I/R-induced hepatocellular damage was attenuated by inhibiting TLR4-mediated inflammatory 125.
• Kudzu root, also known as kuzu, is mostly used as an herb in Traditional Chinese Medicine.
• One study in mice found that kudzu vine extract was highly beneficial in treating alcohol-induced liver damage by scavenging harmful free radicals and boosting the natural antioxidant system (6).
• McLean Hospital has just negotiated a licensing agreement for kudzu root extract with Natural Pharmacia International, Inc., Burlington, MA.
• He worked for many years in mental health and substance abuse facilities in Florida, as well as in home health (medical and psychiatric), and took care of people with medical and addictions problems at The Johns Hopkins Hospital in Baltimore.

1 Participants

Because my drinking levels were so stupendously high in the first place, kudzu did not turn me into a moderate drinker by any stretch of the imagination. Although I’m sure it would have helped me detoxify, I did not use it after I quit drinking. My experience was limited to an experiment that I did years ago to see if taking the herb would reduce my drinking levels.

Previous rodent studies implicated oxidative stress as a key mediator of hangover syndrome, and demonstrated that various antioxidants could suppress the adverse events caused by alcohol exposure 39. Several natural plants and products showed positive effects on alcohol metabolism in animal and human studies. They could upgrade the levels of ADH and ALDH in liver and decrease the concentration of alcohol in blood.

• Dehydroevodiamine, evodiamine and rutaecarpine are the dominant bioactive constituents in Fructus evodiae 50.
• Long-term liver damage and the wound-healing process resulted in liver fibrosis, in which the hepatic stellate cell (HSC) played a key role during fibrogenesis.
• The roots are also resistant to herbicides and it can take 3–10 years of repeated treatments with herbicides before the nutrient reserves of the roots are exhausted.
• It is important to talk to a healthcare professional before taking kudzu, especially if you have liver disease or are taking prescription medication.
• It’s been used for health purposes in Traditional Chinese Medicine for a really long time.

Uses & Effectiveness ?

The protective effect was possibly due to the bioactive antioxidants in fenugreek seeds such as polyphenols 57,58,59. As a result, Trigonela foenum-graecum might have a positive influence on suppressing the abnormalities induced by alcohol in chronic alcohol liver diseases through its antioxidant properties. Two parts (roots and flowers) of Pueraria lobata are usually used in traditional medicine. The flowers have been used to treat the problems caused by alcohol drinking due to their ability to enhance acetaldehyde removal 40. In addition, the flowers of kudzu exerted protective effects against alcohol-induced apoptosis in human neuroblastoma cells 43. Fructus evodiae is a widely used herbal medicine in China with anti-inflammatory and analgetic activities.

Kudzu vine, Pueraria montana, is a dicot leguminous deciduous woody vine that produces tuberous roots and dark brown rope-like stems that climb up to 20 meters (65 feet) high (Fig. 13-10). Young stems are hairy, and the leaves are trifoliate and also hairy (Fig. 13-10A). It produces pretty reddish purple pea-like flowers that lead to the production of dark brown hairy pods. These efforts did not last with just over a million acres of kudzu by 1945. Once federal payments ceased, the kudzu was quickly grazed and plowed under, with farmers having little success figuring out how to make money from it. Forest Service reports that kudzu occupies somewhere around  227,000 acres of forestland.

• The finding that alcohol intake was reduced without affecting desire to use alcohol at first seemed counter-intuitive.
• Kudzu root is the edible part of a trailing vine native to several Asian countries.
• The government runs the voluntary Traditional Herbal Registration (THR) scheme in an effort to combat this problem.

Kudzu, also known as Pueraria Montana, is a climbing vine that belongs to the pea family. This invasive weed is native to East Asia, particularly China, Japan, and Korea, where it has been used for centuries in traditional Chinese medicine. Kudzu is a natural medicine that is extracted from the root of the plant. Natural products for the prevention and treatment of hangover and alcohol use disorder. It’s best to speak with your healthcare provider to determine whether kudzu root could interact with any medications you’re taking. For instance, it may reduce the effectiveness of birth control due to its estrogenic effects (8, 17).

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with KUDZU

Taking kudzu along with medications that also slow clotting might increase the chances of bruising and bleeding. AlcoholAwareness.org provides a platform where you can access various https://ecosoberhouse.com/success-story/erics-success-story/ free resources, including articles, self-assessment tools, and information about local support groups and treatment centers. These resources can be instrumental in guiding you toward effective strategies for overcoming alcoholism. According to some studies, kudzu root may help manage some symptoms of metabolic syndrome. A small 2009 case report involving 16 people with regular cluster headaches provides some anecdotal evidence. Almost 3 in 4 participants had less intense headaches, more than half had fewer headaches, and 1 in 3 had shorter headaches when taking kudzu root.